Psilocybin Therapy & Anorexia Nervosa

Mycophiliac
July 27, 2023

Psilocybin Therapy: A Novel Approach to Treating Anorexia Nervosa

Psilocybin & Anorexia

Anorexia Nervosa is a serious, life-threatening eating disorder characterized by an intense fear of gaining weight and a distorted body image. It can lead to severe health complications, including heart conditions, kidney problems, and even death. Treatment options, such as psychotherapy and medications, have shown varying degrees of success, but they are not universally effective, and relapse rates remain high. This has led researchers to explore novel treatment approaches, one of which is psilocybin therapy.

Psilocybin Therapy & Anorexia

Understanding Psilocybin

Psilocybin is a naturally occurring psychedelic compound produced by more than 200 species of mushrooms, commonly referred to as "magic mushrooms". It has been used for centuries in religious and spiritual rituals due to its psychoactive properties that can induce profound changes in consciousness. For a more detailed understanding of psilocybin, you can refer to the Johns Hopkins University's Center for Psychedelic and Consciousness Research.

Psilocybin's Emerging Role in Psychiatry

Recent studies have shown promising results regarding psilocybin's potential benefits in treating various mental health disorders, such as depression, anxiety, and PTSD. The U.S. Food and Drug Administration (FDA) has even granted psilocybin therapy a "breakthrough therapy" designation for treatment-resistant depression, acknowledging its potential therapeutic value. More information about the breakthrough designation can be found on the U.S. Food and Drug Administration's Breakthrough Therapy page.

The Potential of Psilocybin in Treating Anorexia Nervosa

The altered states of consciousness induced by psilocybin might help patients with anorexia nervosa confront and overcome their fear of gaining weight. University of California at San Diego has studied the effects of magic mushrooms as a therapeutic in treating anorexia nervosa. In their paper, "Psilocybin therapy for females with anorexia nervosa: a phase 1, open-label feasibility study," published in Nature Medicine 2023, the researchers detail the treatment results for an otherwise therapeutic-resistant disorder. Preliminary studies and clinical trials have shown promising results, suggesting that psilocybin therapy could be a powerful tool for treating anorexia nervosa. The exact mechanisms through which psilocybin might alleviate symptoms of anorexia nervosa are still under investigation.

The Challenges and Ethical Considerations

Despite the potential benefits, the use of psilocybin in therapy has its challenges. Psilocybin is classified as a Schedule I substance under the Controlled Substances Act, making it illegal in many jurisdictions. This presents significant hurdles for research. Additionally, the use of a potent psychedelic substance in treatment raises several ethical considerations, especially when treating vulnerable populations. Potential side effects and risks associated with psilocybin use, such as psychological distress and the potential for abuse, must also be carefully considered.

While psilocybin therapy presents a promising new avenue for treating anorexia nervosa, it is vital to approach this potential solution with caution. More research is needed to fully understand the benefits, risks, and mechanisms of action. As we move forward, it is crucial to balance the potential therapeutic benefits of psilocybin with the ethical considerations and potential risks associated with its use. The future of psilocybin therapy will be shaped by ongoing research and necessary policy changes to facilitate its safe and effective use.